Мазин Павел Владимирович
и.о. м.н.с.

Главная Сотрудники Публикации Семинары  и  Конференции Обучение Призы  и  Премии Контакты Англ


Образование и опыт работы:

• 2010 – н.в. стажер-исследователь ИППИ РАН
• 2012. Школа Анализа Геномных Данных (CSHL), Москва, 2-11 июля 2012
• 2008. Выпускник Факультета Биоинженении и Биоинформатики МГУ
• 2006 – 2008. Факультет Биоинженении и Биоинформатики МГУ
• 2002 – 2006. Химический Факультет МГУ

Научные интересы:

• альтернативный сплайсинг
• геномика
• эволюция человека
• развитие мозга


Публикации:

Mazin, Pavel; Fisunov, Gleb; Gorbachev, Alexey; Kapitskaya, Kristina; Altukhov, Ilya; Semashko, Tatiana; Alexeev, Dmitry; Govorun, Vadim. Transcriptome analysis reveals novel regulatory mechanisms in a genome-reduced bacterium. Nucleic Acids Res. 2014. 42(21):13254-68. PubMed 
Gorbachev AY, Fisunov GY, Izraelson M, Evsyutina DV, Mazin PV, Alexeev DG, Pobeguts OV, Gorshkova TN, Kovalchuk SI, Kamashev DE, Govorun VM. DNA repair in Mycoplasma gallisepticum.BMC Genomics. 2013 Oct 23;14:726. PubMed 

P. Mazin, J. Xiong, X. Liu, Zh. Yan, X. Zhang, M. Li, L. He, M. Somel, Yu. Yuan, Y. Ph. Chen, N. Li, Y. Hu, N. Fu, Zh. Ning, R. Zeng, H. Y., W. Chen, M. Gelfand, Ph. Khaitovich. Widespread splicing changes in human brain development and aging.Algorithms Mol Biol. 2010, 5: 29. PubMed 

P.V. Mazin, M.S. Gelfand, A.A. Mironov, A.B. Rakhmaninova, A.R. Rubinov, R.B. Russell, O.V. Kalinina. An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies. Algorithms Mol Biol. 2010, 5: 29. PubMed  PDF

E.V. Antipov, A.G. Borzenko, V.M. Denisov, A.Yu. Filatov, V.V. Ivanov, S.M. Kazakov, P.V. Mazin, V.M. Mazin, V.I. Shtanov, D.A. Simakov, G.A. Tsirlina, S.Yu. Vassiliev, Yu.A. Velikodny. Electrochemical behavior of metals and binary alloys in cryolite-alumina melts. Light metals 2006, 403-408. PDF


Конференции:

• Mazin P. Expression regulation of desiccation-resistance genes in Polypedilum vanderplanki (oral presentation). Moscow Conference on Computational Molecular Biology (MCCMB) 2015. Moscow, Russia.
• Pavel Mazin. Quantification of alternative splicing using RNA-seq. Postgenome-2014. 29.10-01.11.2014 Kazan, Russia.
• Pavel Mazin, Gleb Fisunov, Alexey Gorbachev, Dmitry Alexeev. Regulation without regulators: transcriptom of Mycoplasma gallisepticum (poster presentation). Information Technologies and Systems (ITaS) 2014. September 1-5, 2014, Russia.
• P. Mazin, P. Khaitovich, M. Gelfand. Widespread differences in age-related splicing patterns between higher primates. Information Technologies and Systems (ITaS). August 19 – 25, 2012, Petrozavodsk, Russia (poster presentation)
• P. Mazin, P. Khaitovich. Age-related splicing changes in human, chimpanzee and monkey brains. Conf for young scientists, Molecular and cell biology: practical aspects, April 13, 2012, Moscow (oral presentation)
• P. Mazin, M. Gelfand, P. Khaitovich. Age changes and tissue differences of alternative splicing in the primate brain. The 8th Winter Symposium on Chemometrics, Moscow, Febrary 27 - March 2, 2012 (oral presentation)
• П.А. Мазин, Е.А. Храмеева, А.А. Миронов, Ф. Хайтович, М.С. Гельфанд. Пространственная структура хроматина, эпигенетика и альтернативный сплайсинг. II международная научно-практическая конференция «Постгеномные методы анализа в биологии, лабораторной и клиничекой медицине: геномика, протеомика, биоинформатика». Новосибирск. 14-17.11.2011 (пленарный доклад)
• М.С.Гельфанд, П.А.Мазин, Ф. Хайтович. Возрастные изменения альтернативного спласинга в мозге у приматов. Фундаментальные науки медицине. Москва, 2011
• P. Mazin, P.Khaitovich. Splicing differences during primate brain development. Information Technologies and Systems (ITaS). October 2 – 7, 2011, Gelendzhik, Russia (oral presentation)
• P. Mazin, M. Gelfand, P. Khaitovich. Splicing differences in primate brain development. Moscow Conference on Computational Molecular Biology `11 (poster presentation)
• P. Mazin, M. Gelfand, P. Khaitovich. Splicing changes in human brain over the course of lifespan. CSH-Asia Сonference “Computational Biology”. Suzhou, China, 27.09-1.10.2010 (poster presintation)
• A.A. Adzhubei, A.V. Vlasova, P.V. Mazin. Qasmod: Protein Model Quality Assessment Suite. The Seventh International Conference on Bioinformatics of Genome Regulation and Structure (BGRS'2010), Novosibirsk, Russia, June 20-27, 2010 (poster presentation)
• P.V. Mazin, P.Khaitovich, A.A. Mironov, M.S. Gelfand Investigation of age related alternative splicing changes in human brain using solexa sequencing. Moscow Conference on Computational Molecular Biology `09 (poster presentation)
• P.V. Mazin, O.V.Kalinina, A.B. Rakhmaninova, A.A. Mironov, M.S. Gelfand. SDPfox - a Web-server for protein substrate specificity analysis. Information Technologies and Systems (ITaS). 266-267. September 29 – October 3, 2008, Gelendzhik, Russia (oral presentation)
• P.V. Mazin, A.A. Mironov, A.B. Rakhmaninova, M.S. Gelfand, O.V.Kalinina. SDPfox: A tool to predict protein specificity and specificity determinants from multiple sequence alignment. The 6th International Conference on Bioinformatics of Genome Regulation and Structure (BGRS'2008), Novosibirsk, Russia, June 22-28, 2008 (poster presentation)
• P. V. Mazin, O. V. Kalinina. SDPfox – a Web-server for prediction of protein specificity and specificity determinants from multiple sequence alignment. The XV Int Scientific Conf for undergraduate and postgraduate students, and young scientists “Lomonossov”. 11 - 14 April 2008 (poster presentation)
• P.V. Mazin. SDPclust — program package for protein substrate specificity prediction. Information Technologies and Systems (ItaS). P 269-270. September 18-21, 2007, Zvenigorod, Russia (poster presentation)
• P.V. Mazin A.B.Rakhmaninova, O.V. Kalinina. SDPclust: a new tool for prediction protein specificity in MPA. Moscow Conference on Computational Molecular Biology `07 (poster presentation)
• P. V. Mazin, O. V. Kalinina. SDPlight – a fast method for searching positions that determine specificity in protein alignments. The XIV Int Scientific Conf for undergraduate and postgraduate students, and young scientists “Lomonossov”. 11 - 14 April 2007 (poster presentation)